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A Review of Novel Antidepressants: A Guide for Clinicians

    https://pubmed.ncbi.nlm.nih.gov/31106085/
    Depression may not be caused by the simple deficiency of serotonin in the brain, but rather a complex interplay of various neurotransmitters including serotonin, norepinephrine, glutamate, and histamine at certain brain areas. The above …

Neurotransmitter targeting in the treatment of depression

    https://pubmed.ncbi.nlm.nih.gov/24191974/
    Medications that increase norepinephrine or dopamine neurotransmission may improve several common residual symptoms left after treatment with serotonin-specific agents. …

Mechanisms of action of antidepressants: from …

    https://pubmed.ncbi.nlm.nih.gov/15683730/
    Recent reports suggest that antidepressants can induce neurogenesis in the adult brain, although the mechanisms involved are not clearly understood. In this review, we describe …

Depression: How effective are antidepressants? - NCBI …

    https://www.ncbi.nlm.nih.gov/books/NBK361016/
    They are effective in moderate, severe and chronic depression, but probably not in mild cases. They can also have side …

Atypical Neurotransmitters and the Neurobiology of Depression

    https://pubmed.ncbi.nlm.nih.gov/26350337/
    Since the first report that the mechanism of action of antidepressants involves the facilitation of monoaminergic neurotransmission in the brain in the 1960s, the leading hypothesis about the neurobiology of depression has been the so …

Antidepressants - StatPearls - NCBI Bookshelf

    https://www.ncbi.nlm.nih.gov/books/NBK538182/
    The antidepressants all work slightly differently and target certain neurotransmitters to modulate mood and behavior. All currently …

Physiology, Neurotransmitters - StatPearls - NCBI …

    https://www.ncbi.nlm.nih.gov/books/NBK539894/
    There are a number of neurotransmitters used by the body for different functions, including acetylcholine, glutamate, GABA, glycine, dopamine, norepinephrine, and serotonin. Glutamate is the principal …

Selective serotonin reuptake inhibitors (SSRIs) - Mayo …

    https://www.mayoclinic.org/diseases-conditions/depression/in-depth/ssris/art-20044825
    SSRIs treat depression by increasing levels of serotonin in the brain. Serotonin is one of the chemical messengers (neurotransmitters) that carry signals between brain nerve cells …

Tricyclic Antidepressants - StatPearls - NCBI Bookshelf

    https://www.ncbi.nlm.nih.gov/books/NBK557791/
    Tricyclic antidepressants (TCAs) generally have a narrow therapeutic index and, therefore, are prone to induce toxicity if intentional overdose occurs. They have demonstrated higher rates of death per one …

Serotonin and norepinephrine reuptake inhibitors (SNRIs)

    https://www.mayoclinic.org/diseases-conditions/depression/in-depth/antidepressants/art-20044970
    SNRIs ease depression by affecting chemical messengers (neurotransmitters) used to communicate between brain cells. Like most …



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