Dehp In Medical Devices An Exposure And Toxicity Assessment

An update on the hazard of and exposure to …

https://pubmed.ncbi.nlm.nih.gov/33006299/

Safety Assessment of Di(2-ethylhexyl)phthalate (DEHP) …

https://noharm.org/sites/default/files/lib/downloads/pvc/Safety_Assessment_of_DEHP.pdf

exposed to DEHP, a safety assessment has been conducted by the FDA Center for Devices and Radiological Health (CDRH) to provide risk managers with information …

Di(2-ethylhexyl)phthalate (DEHP): human metabolism …

https://pubmed.ncbi.nlm.nih.gov/16466535/

Abstract. Di (2-ethylhexyl)phthalate (DEHP) is a reproductive and developmental toxicant in animals and a suspected endocrine modulator in humans. There is widespread exposure …

SUMMARY OF THE FDA SAFETY ASSESSMENT OF …

https://noharm.org/sites/default/files/lib/downloads/pvc/Sum_FDA_Safety_Assess_DEHP.pdf

safety assessment on DEHP. DEHP is used to soften PVC medical devices such as bags and tubing. DEHP has been shown to produce a wide range of adverse effects in …

CDRH Scientific Perspective on Chemical Analysis …

https://www.toxicology.org/groups/ss/MDCPSS/docs/Webinar-SOT-MDCPSS-May22-2019-Slides-final.pdf

Background: Why Chemical Analysis and Toxicological Risk Assessment 2016 CDRH Biocompatibility Guidance “Inherent in the review of medical devices is an …

THE SAFETY OF MEDICAL DEVICES …

https://ec.europa.eu/health/archive/ph_risk/committees/04_scenihr/docs/scenihr_o_014.pdf

The safety of medical devices containing DEHP-plasticized PVC or other plasticizers on neonates and other groups possibly at risk 4 ABSTRACT The Scientific Committee on …

DEHP phthalates in medical devices - GOV.UK

https://www.gov.uk/government/publications/dehp-phthalates-in-medical-devices/dehp-phthalates-in-medical-devices

Phthalates are chemicals added to polyvinyl chloride ( PVC) plastic to make it softer and more flexible. Di (2-ethylhexyl) phthalate ( DEHP) is the type used the most in …

Phthalates: Toxicology and exposure - ScienceDirect

https://www.sciencedirect.com/science/article/pii/S1438463907001125

Intravenous exposure to DEHP from selected medical procedures using medical devices of PVC containing DEHP (modified from US FDA, 2002) Therefore, …

Final opinion on DEHP - health.ec.europa.eu

https://health.ec.europa.eu/other-pages/health-sc-basic-page/final-opinion-dehp_en

Examples of medical procedures with a potential for high exposure to DEHP are multiple procedures in preterm neonates, haemodialysis, heart transplantation or coronary artery …

Dehp In Medical Devices An Exposure And Toxicity Assessment

https://dayofdifference.org.au/d-medical/dehp-in-medical-devices-an-exposure-and-toxicity-assessment.html

in humans is qualitatively independent on the exposure routes (oral or i.v.). DEHP has a low oral acute toxicity (LD 50>25 g/kg in rats and mice). Lower LD 50 values were obtained …