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Innovation, Regulation, and the FDA | NEJM

    https://www.nejm.org/doi/full/10.1056/NEJMsa1007467
    The FDA can become more transparent, so that knowledge and insights can be shared and the field of drug discovery can move forward more quickly. Regulatory …

Regulating Off-Label Drug Use — Rethinking the …

    https://www.nejm.org/doi/full/10.1056/NEJMp0802107
    The Food and Drug Administration (FDA) provides a barrier to market entry and use of unproven and unsafe products. …

FDA Approval and Regulation of Pharmaceuticals, 1983 …

    https://pubmed.ncbi.nlm.nih.gov/31935033/
    Conclusions and relevance: Over the last 4 decades, the approval and regulation processes for pharmaceutical agents have evolved and increased in …

Emerging Regulatory Affairs Trends in 2022

    https://www.northeastern.edu/graduate/blog/regulatory-affairs-trends/
    Regulatory affairs professionals play an essential role within the lifecycle of drugs, biologics, and medical devices, helping …

Regulation and Innovation: Role of Regulatory Science …

    https://pubmed.ncbi.nlm.nih.gov/30883715/
    Regulatory science is defined as science and research intended to inform decision making in a regulatory framework. This issue of Clinical Pharmacology & Therapeutics and the …

FDA Approval and Regulation of Pharmaceuticals, 1983 …

    https://jamanetwork.com/journals/jama/fullarticle/2758605
    After the 1962 Kefauver-Harris Drug Amendments prohibited marketing without explicit FDA approval based on documentation of efficacy, budget limitations made it impossible for …

Advancing Regulatory Science at FDA - Food and …

    https://www.fda.gov/media/145001/download
    FDA advances regulatory science by developing the tools and methods, and obtaining the data needed to speed innovation, improve regulatory evaluation, and facilitate availability …

Pharmaceuticals Regulation - an overview

    https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/pharmaceuticals-regulation
    Pharmaceutical regulations, or medicines regulations, have been defined as the combination of legal, administrative, and technical measures that governments …

FDA Regulation of Medical Devices—Moving Beyond the …

    https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2786216
    Increased awareness of the harms of limited US Food and Drug Administration (FDA) regulation led to the first statutory premarket regulation of medical devices. Full Text …

Fact Sheet: FDA at a Glance | FDA - U.S. Food and …

    https://www.fda.gov/about-fda/fda-basics/fact-sheet-fda-glance
    About 78 percent of active pharmaceutical ingredients manufacturers are located outside of the U.S. FDA-regulated products account for 15 percent of U.S. imports …



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