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Guidelines for Endpoints in Animal Study Proposals

    https://oacu.oir.nih.gov/system/files/media/file/2022-04/b13_endpoints_guidelines.pdf
    studies, and cancer research. The following guidelines are suggested to assist the Animal Care and Use Committees in reviewing proposals with death or moribundity as endpoints. Required Information for ASPs Utilizing Death or Moribundity as an Endpoint: 1. The …

Defining Humane Endpoints - Institutional Animal Care …

    https://research.wayne.edu/iacuc/defininghumaneendpoints
    IACUC Guidelines. Humane endpoints must be clearly defined and based on objective criteria (See table below for examples). They are study-specific and should be formulated …

Center for Biomedical Research / IACUC Standard …

    https://und.edu/research/biomedical-research/_files/docs/humane-endpoints.pdf
    Canadian Council on Animal Care (1998), Guidelines on: Choosing an appropriate endpoint in experiments using animals for research, teaching and testing. Ottawa, …

Establishing Humane Endpoints - UCI Office of Research

    https://research.uci.edu/animal-care-and-use/policies-and-guidance/establishing-humane-endpoints/
    Establishing Humane Endpoints Overview The importance of minimizing discomfort, pain or distress that animals may experience during the conduct of biomedical research is well …

Humane Endpoints in Animal Research | Research at …

    https://www.research.psu.edu/newanimal/experimental-guidelines/defining-humane-endpoints
    Humane endpoints refer to one or more predetermined physiological or behavioral signs that define the point at which an experimental animal’s pain and/or distress is terminated, …

Humane Endpoints | Research at Penn State

    https://www.research.psu.edu/animalresourceprogram/experimental-guidelines/humane-endpoints
    USDA National Agricultural Library. Canadian Council on Animal Care. Investigators should include a precise definition of the humane endpoint (s), including specific assessment …

Humane Endpoints for Infectious Disease Animal Models

    https://academic.oup.com/ilarjournal/article/41/2/99/749074
    Introduction. The obligation to minimize or eliminate unnecessary pain and distress animals may experience when they are used in biomedical research, …

Humane Endpoints - ILAR

    https://www.humane-endpoints.info/en/ilar
    Particularly relevant with respect to humane endpoints are the issues which can be found in these ILAR- journals, for example: ILAR Journal 41 (2), 2000: Humane Endpoints for …

Humane endpoints in animal experimentation for …

    https://www.researchgate.net/publication/228604657_Humane_endpoints_in_animal_experimentation_for_biomedical_research_ethical_legal_and_practical_aspects
    The reasons for implementing humane endpoints are discussed and include: when the scienti®c results will no longer be valid; when there is a lack of proportionality between suffering and bene®t ...

Humane endpoints for laboratory animals used in …

    https://pubmed.ncbi.nlm.nih.gov/12388849/
    Abstract. Laboratory animals are used for regulatory testing to assess the safety, efficacy, and/or potential adverse health effects of new chemicals and products such as vaccines, …



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