Humane Endpoints In Animal Experiments For Biomedical Research

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Guidelines for Endpoints in Animal Study Proposals

https://oacu.oir.nih.gov/system/files/media/file/2022-04/b13_endpoints_guidelines.pdf

Where pain or distress is a necessary part of the study, a humane endpoint must be used and approvedby the ACUC.1 A humane endpoint is the earliest scientifically justified point at which pain or distress in an experimental animal can be prevented, terminated, or relieved, while meeting the scientific aims andobjectives of the study.

Humane endpoints in animal …

https://www.researchgate.net/publication/228604657_Humane_endpoints_in_animal_experimentation_for_biomedical_research_ethical_legal_and_practical_aspects

The reasons for implementing humane endpoints are discussed and include: when the scienti®c …

Refining humane endpoints in mouse models of disease …

https://pubmed.ncbi.nlm.nih.gov/31026040/

Ideally, humane endpoints allow for early termination of experiments by minimizing an animal's discomfort, distress and pain, while ensuring that scientific objectives are …

How to determine humane endpoints for …

https://www.nature.com/articles/laban.908

Metrics. The website “Humane endpoints in laboratory animal experimentation” is a rich resource with information to help researchers define and implement …

A review on humane endpoints in animal …

https://www.researchgate.net/publication/351152326_A_review_on_humane_endpoints_in_animal_experimentation_for_biomedical_research

Humane endpoints terminate pain and distress in laboratory animals, which are experimented in painful procedures and an involuntary manner. This study was going …

Humane Endpoints for Laboratory Animals Used in …

https://academic.oup.com/ilarjournal/article/43/Suppl_1/S31/756764

Guidelines for choosing appropriate endpoints in experiments using animals for research, testing, and teaching have also been developed ( CCAC 1998; OECD …

Humane Endpoints in Animal Research | Research at …

https://www.research.psu.edu/newanimal/experimental-guidelines/defining-humane-endpoints

Humane endpoints refer to one or more predetermined physiological or behavioral signs that define the point at which an experimental animal’s pain and/or distress is terminated, …

IACUC GUIDELINE: HUMANE EXPERIMENTAL …

https://www.research.ucsb.edu/sites/default/files/policies/iacuc/ucsbhumaneendpoints.pdf

Humane Endpoints Animal studies may involve procedures that cause pain or distress to the animals, which cannot be alleviated with analgesia, anesthesia, sedation, or palliative …

Humane Endpoints | Research at Penn State

https://www.research.psu.edu/animalresourceprogram/experimental-guidelines/humane-endpoints

USDA National Agricultural Library. Canadian Council on Animal Care. Investigators should include a precise definition of the humane endpoint (s), including specific assessment …

Humane endpoints in animal experiments for biomedical …

https://www.semanticscholar.org/paper/Humane-endpoints-in-animal-experiments-for-research-Hendriksen-Morton/39a90f6d94c0880b9eb32f49e7d132768eb3dbc0

Humane endpoints in animal experiments for biomedical research. C. Hendriksen, D. Morton. Published 1999. Psychology. Proceedings of the International CO'1ference, 22 …

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