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Humanized mice in translational biomedical research

    https://pubmed.ncbi.nlm.nih.gov/17259968/
    Abstract. The culmination of decades of research on humanized mice is leading to advances in our understanding of human haematopoiesis, innate and adaptive immunity, …

Humanized mice in translational biomedical research

    https://www.nature.com/articles/nri2017/
    Humanized mice in translational biomedical research There is a growing need for animal models to carry out in vivo studies of human biological systems without putting...

The humanized mouse: Emerging translational potential

    https://pubmed.ncbi.nlm.nih.gov/32275343/
    The humanized mouse (HM) has emerged as a valuable animal model in cancer research. Engrafted with components of a human immune system and subsequently implanted with …

Humanized mice in translational biomedical research

    https://www.semanticscholar.org/paper/Humanized-mice-in-translational-biomedical-research-Shultz-Ishikawa/8effdcd48425c2045e6a6519e66aab9f3caec6ac
    Humanized mice in translational biomedical research. The culmination of decades of research on humanized mice is leading to advances in our understanding of …

Humanized mice: A brief overview on their diverse …

    https://pubmed.ncbi.nlm.nih.gov/28543438/
    Abstract. Model animals naturally differ from humans in various respects and results from the former are not directly translatable to the latter. One approach to address this issue …

Humanized Mice for the Study of Immuno-Oncology

    https://pubmed.ncbi.nlm.nih.gov/30077656/
    In this review, we discuss recent advances in the 'humanization' of mouse models to improve the quality of human immune cell reconstitution. We also highlight new insights …

What is a Humanized Mouse? Remaking the Species …

    https://journals.sagepub.com/doi/10.1177/1357034X12446378
    The humanized mouse is a complex experimental object in which mice, rendered immunodeficient through genetic alteration, are engrafted with human stem …

Frontiers | Humanized Rodent Models for Cancer Research

    https://www.frontiersin.org/articles/10.3389/fonc.2020.01696/full
    Humanized mice are novel animal models designed to address some of these concerns, thereby making them an attractive alternative for biomedical research ( 10 ). Briefly, humanized mice are …

Shultz, L.D. , Ishikawa, F. & Greiner, D.L. Humanized …

    https://www.researchgate.net/publication/6544112_Shultz_LD_Ishikawa_F_Greiner_DL_Humanized_mice_in_translational_biomedical_research_Nat_Rev_Immunol_7_118-130
    The culmination of decades of research on humanized mice is leading to advances in our understanding of human haematopoiesis, innate and adaptive immunity, …

Humanized Mice Are Instrumental to the Study of …

    https://pubmed.ncbi.nlm.nih.gov/30631319/
    Humanized Mice Are Instrumental to the Study of Plasmodium falciparum Infection. Research using humanized mice has advanced our knowledge and …



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