Intercurrent Medical Event

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Rethinking intercurrent events in defining estimands for …

https://pubmed.ncbi.nlm.nih.gov/35850542/

A key issue is the handling of intercurrent (i.e. post-randomisation) events (ICEs) which affect interpretation of or preclude measurement of the intended final outcome. We consider common ICEs including treatment changes and treatment extension, poor …

ASA-FDA 2018: ICH E9 (R1), Estimands, Intercurrent Events, and ...

https://www.prometrika.com/thought-leadership/asa-fda-2018-ich-e9-r1-estimands-intercurrent-events-and-sensitivity-analysis/

Specifically, intercurrent events, defined as events that occur after treatment initiation and either preclude observation of the variable or affect its …

Estimands and Intercurrent Events - SDC

https://www.sdcclinical.com/wp-content/uploads/2018/05/SDC-Fact-Sheet-Estimands-and-Intercurrent-Events.pdf

Intercurrent Events (IcE) › Occur After Treatment Initiation and preclude observation or affect interpretation of the variable › Examples Include use of a rescue medication, …

Intercurrent | definition of intercurrent by Medical dictionary

https://medical-dictionary.thefreedictionary.com/intercurrent

Intercurrent | definition of intercurrent by Medical dictionary intercurrent Also found in: Dictionary. intercurrent [ in″ter-kur´ent] pertaining to a process that occurs during the …

Estimands – What you need to know - Quanticate

https://www.quanticate.com/blog/estimands-clinical-trials

Intercurrent Definition & Meaning - Merriam-Webster

https://www.merriam-webster.com/dictionary/intercurrent

: occurring during and modifying the course of another disease an intercurrent infection Word History Etymology Latin intercurrent-, intercurrens, present participle of …

Intercurrent disease | definition of intercurrent disease by …

https://medical-dictionary.thefreedictionary.com/intercurrent+disease

intercurrent. pertaining to a process that occurs during the course of some other event. intercurrent disease a disease occurring during the course of another disease with which …

E9(R1) Statistical Principles for Clinical Trials: …

https://www.fda.gov/media/108698/download

Intercurrent events need to be considered in the descriptionof a 130 treatment effect on a variable of interest because both the value of the variable and the 131 occurrence of …

Medical Definition of Intercurrent disease - MedicineNet

https://www.medicinenet.com/intercurrent_disease/definition.htm

Intercurrent disease: A disease that intervenes during the course of another disease. A patient with AIDS may develop an intercurrent bout of pneumonia. …

Intercurrent medical diseases: incidence and effects on …

https://pubmed.ncbi.nlm.nih.gov/16794640/

The prevalent age of intercurrent medical diseases was 60 years and above. The incidence of common illnesses was: hypertension (41.86% ), diabetes (14.2% ), upper …

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