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Bucillamine, a thiol antioxidant, prevents …

    https://www.pnas.org/doi/10.1073/pnas.132026099
    Lyophilized bucillamine (purity >99.9%) was provided by Keystone Biomedical (Los Angeles). Just before use, it was reconstituted with sterile water, diluted in 0.45% (wt/vol) saline to a concentration of 50 mg/ml, and diluted further in University of Wisconsin (UW) solution.

Keystone Biomedical, Inc. | SBIR.gov

    https://www.sbir.gov/sbc/keystone-biomedical-inc
    bucillamine and radiocontrast- induced nephropathy DESCRIPTION (provided by applicant): It is proposed to test in animal models the potential efficacy of administration …

Bucillamine: A Potent Thiol Donor with Multiple …

    https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1527-3466.2003.tb00107.x
    Bucillamine has potential to attenuate or prevent damage during myocardial infarction, cardiac surgery and organ transplantation. Bucillamine, a cysteine derivative that …

Bucillamine in Treatment of Patients With COVID-19

    https://clinicaltrials.gov/ct2/show/NCT04504734
    Detailed Description: This is a Phase 3, multi-center, randomized, double blind, placebo controlled, clinical study of bucillamine (2 dosage levels) in patients with …

Bucillamine: A Potent Thiol Donor with Multiple Clinical …

    https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1527-3466.2003.tb00107.x?sid=nlm%3Apubmed
    Dr. Horwitz is an officer and major stockholder of Keystone Biomedical Inc., which holds patent rights on certain potential uses of bucillamine that are cited in this …

Bucillamine and Radiocontrast - Induced Nephropathy

    https://grantome.com/grant/NIH/R41-DK072644-01
    It is proposed to test in animal models the potential efficacy of administration of bucillamine a potent antioxidant and immunomodulating agent for prevention o...

Bucillamine, a thiol antioxidant, prevents …

    https://www.pnas.org/doi/pdf/10.1073/pnas.132026099
    Bucillamine, a thiol antioxidant, prevents transplantation-associated reperfusion injury Farin Amersi*, Sally K. Nelson†, Xiu Da Shen*, Hirohisa Kato*, Judy Melinek*, Jerzy W. Kupiec …

Bucillamine: A Potent Thiol Donor with Multiple Clinical …

    https://www.researchgate.net/publication/6644985_Bucillamine_A_Potent_Thiol_Donor_with_Multiple_Clinical_Applications
    Bucillamine, a... | Find, read and cite all the research you need on ResearchGate ... Powdered bucillamine (>99% purity) was purchased from Keystone …

BUCILLAMINE AND RADIOCONTRAST - INDUCED …

    https://www.sbir.gov/sbirsearch/detail/209724

Thiol Antioxidants Inhibit the Adjuvant Effects of …

    https://cfpub.epa.gov/ncer_abstracts/index.cfm/fuseaction/display.files/fileID/13999
    2 M.A.H. and L.D.H. are major stockholders in Keystone Biomedical, Inc., which provided the bucillamine for this study. 3 Address correspondence and reprint requests to Dr. …



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