Medical Applications Of Intermediate Filaments

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Roles and potential clinical applications of intermediate …

https://pubmed.ncbi.nlm.nih.gov/25976260/

Astrocytes express glial fibrillary acidic protein (GFAP), whereas different neuron types contain neurofilament proteins, α-internexin, or peripherin. These proteins are often downregulated in brain cancer. In addition, brain cancer cells may also contain vimentin, …

Intermediate Filament Proteins and Their …

https://www.nejm.org/doi/full/10.1056/NEJMra040319

Alterations in Intermediate Filament Proteins in Disease States. Intermediate filament proteins are regulated by several post …

Intermediate filament: structure, function, and …

https://pubmed.ncbi.nlm.nih.gov/24591257/

Intermediate filament (IF) constitutes an important cytoskeletal component in nearly all the vertebrate cells. IFs are present both in the cytoplasm and in the nucleus. They play an …

Intermediate Filaments - The Cell - NCBI …

https://www.ncbi.nlm.nih.gov/books/NBK9834/

All of the intermediate filament proteins have a central α-helical rod domain of approximately 310 amino acids (350 amino acids in …

Intermediate Filaments - Definition, Structure, …

https://microbiologynote.com/intermediate-filaments/

IFs are especially abundant in areas where cells are subjected to mechanical stress, such as in epithelia, where they are interconnected at desmosomal junctions, along the length of axons, …

12.2: Intermediate Filaments - Biology LibreTexts

https://bio.libretexts.org/Bookshelves/Cell_and_Molecular_Biology/Book%3A_Cells_-_Molecules_and_Mechanisms_(Wong)/12%3A_Cytoskeleton/12.02%3A_Intermediate_Filaments

This then coils around another filamentous subunit to form a coiled-coil dimer, or protofilament. These protofilaments then interact to form tetramers, which are …

Cell - Intermediate filaments | Britannica

https://www.britannica.com/science/cell-biology/Intermediate-filaments

Intermediate filaments are so named because they are thicker than actin filaments and thinner than microtubules or muscle myosin filaments. The subunits of intermediate …

Intermediate Filaments | Clinical Gate

https://clinicalgate.com/intermediate-filaments/

All intermediate filament proteins possess an α-helical coiled-coil domain that forms the core of the filaments, while the flanking N- and C-terminal domains vary …

Intermediate Filaments: Structure and …

https://study.com/academy/lesson/intermediate-filaments-definition-function-structure.html

Intermediate Filaments Function The main function of intermediate filaments is to provide support and structure for cells. The intermediate filaments are a permanent part of the …