Medical Information On Cpa1

Human CPA1 mutation causes digestive enzyme …

https://pubmed.ncbi.nlm.nih.gov/30045879/

Recently, loss-of-function mutations in CPA1, which encodes the digestive enzyme carboxypeptidase A1, were described in sporadic early onset cases and in hereditary pancreatitis. Mutation-induced misfolding of CPA1 and associated endoplasmic …

Carboxypeptidase A1 (CPA1) Immunohistochemistry Is …

https://journals.lww.com/ajsp/Fulltext/2022/01000/Carboxypeptidase_A1__CPA1__Immunohistochemistry_Is.18.aspx

Carboxypeptidase A1 (CPA1) is a zinc metalloprotease that is produced in pancreatic acinar cells and plays a role in cleaving C-terminal branched-chain and aromatic amino acids …

Pancreas Panel | Pancreas Disease Test Catalog

https://www.cincinnatichildrens.org/service/h/heritable-pancreatic-diseases-genetic-testing/tests-offered/panel

Human CPA1 mutation causes digestive enzyme …

https://gut.bmj.com/content/68/2/301

Objective Chronic pancreatitis is a progressive, relapsing inflammatory disorder of the pancreas, which often develops in the background of genetic …

Carboxypeptidase A1 (CPA1) Immunohistochemistry Is …

https://pubmed.ncbi.nlm.nih.gov/34889867/

CPA1 was strongly expressed in acinar cells of all normal pancreas samples but not in any other normal tissues. CPA1 immunostaining was detected in …

CPA1 | MENDELIAN.CO

https://www.mendelian.co/genes/cpa1

Patients with CPA1 gene alterations may also develop some of the following symptoms and phenotypes: Commonly - More than 50% cases; Abnormal enzyme/coenzyme activity; …

Mutations in the pancreatic secretory enzymes CPA1 …

https://www.pnas.org/doi/10.1073/pnas.1720588115

Much of the inherited susceptibility to pancreatic cancer remains unexplained. Germline variants that cause protein misfolding and impaired secretion of pancreatic …

A novel p.Ser282Pro CPA1 variant is associated with …

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5933945/

(A) Secretion of CPA1 to the growth medium was analyzed by SDS-PAGE and Coomassie Blue staining. Samples were loaded in duplicates. CPA1 activity in the conditioned …

CPA Healthcare Abbreviation Meaning - All Acronyms

https://www.allacronyms.com/CPA/healthcare

Healthcare CPA abbreviation meaning defined here. What does CPA stand for in Healthcare? Get the top CPA abbreviation related to Healthcare.

Anti-CPA1 Antibodies | Invitrogen - Thermo Fisher Scientific

https://www.thermofisher.com/antibody/gene/CPA1

CPA1, also known as CPA, is a 419 amino acid secreted monomeric protein that is highly expressed in pancreatic tissue. Functioning as a pancreatic exopeptidase, CPA1 uses …