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Response-Guided Telaprevir Combination Treatment for …

    https://www.nejm.org/doi/full/10.1056/NEJMoa1014463
    We enrolled patients with chronic infection with HCV genotype 1 who had not previously received treatment. All patients received telaprevir at a dose of 750 mg every 8 hours, peginterferon alfa-2a at a dose of 180 μg per week, and ribavirin at a dose of 1000 to 1200 mg per day, for 12 weeks (T12PR12), followed by … See more

Our Science | Clinical Trials & Data Sharing - Vertex

    https://www.vrtx.com/our-science/clinical-trials-data-sharing/
    Clinical trials are carefully designed research studies in humans that evaluate the safety and efficacy of an investigational medicine. If you’re interested in participating in a Vertex …

Telaprevir - Wikipedia

    https://en.wikipedia.org/wiki/Telaprevir

    A Safety and Efficacy Study of the Combination of VX …

      https://clinicaltrials.gov/ct2/show/NCT01080222
      The purpose of this study is to assess the safety and efficacy of combination treatment with VX-222 and telaprevir administered for 12 weeks with and without …

    VX-222 + Telaprevir + Ribavirin for 12 or 16 Weeks in …

      https://clinicaltrials.gov/ct2/show/NCT01581138
      VX-222 + Telaprevir + Ribavirin for 12 or 16 Weeks in Treatment-Naive Subjects With Genotype 1a Hepatitis C. The safety and scientific validity of this study is …

    Vertex Begins Study of 2 Oral HCV Drugs Telaprevir

      https://www.natap.org/2010/HCV/030210_01.htm
      Telaprevir is an investigational oral inhibitor of HCV protease, an enzyme essential for viral replication, and is being evaluated as part of a global Phase 3 registration program in …

    A Study of Telaprevir (VX-950), Pegasys and Copegus in …

      https://www.clinicaltrials.gov/ct2/show/NCT00420784
      The PROVE3 trial is a partially double blinded, randomized, Phase 2 research study of an investigational drug, Telaprevir (VX-950) or Placebo, with Pegylated …

    A Study Evaluating Efficacy and Safety of VX-548 for …

      https://clinicaltrials.gov/ct2/show/NCT04977336
      A Study Evaluating Efficacy and Safety of VX-548 for Acute Pain After a Bunionectomy. The safety and scientific validity of this study is the responsibility of the …

    A Study Evaluating Efficacy and Safety of VX-548 for …

      https://clinicaltrials.gov/ct2/show/NCT05034952
      Primary Outcome Measures : Time-weighted sum of the Pain Intensity Difference (SPID) as Recorded on a Numeric Pain Rating Scale (NPRS) at Rest 0 to 48 …

    A Phase 3 Study of Telaprevir in Combination With …

      https://clinicaltrials.gov/ct2/show/NCT00627926
      Number of Subjects Achieving Rapid Viral Response (RVR), Demonstrated by Achieving Undetectable HCV RNA 4 Weeks After Starting Study Treatment [ Time …



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