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Saxitoxin - Wikipedia

    https://en.wikipedia.org/wiki/Saxitoxin
    The medical and environmental importance of saxitoxin derives from the consumption of contaminated shellfish and certain finfish which can concentrate the toxin from dinoflagellates or cyanobacteria. The blocking of neuronal sodium channels which occurs in PSP produces a … See more

Saxitoxin - an overview | ScienceDirect Topics

    https://www.sciencedirect.com/topics/neuroscience/saxitoxin
    Saxitoxin interrupts nerve transmissions by binding to voltage-gated sodium channels. Positively charged guanidinium groups of saxitoxin interact with negatively …

Saxitoxin - an overview | ScienceDirect Topics

    https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/saxitoxin
    Saxitoxin (STX), a highly selective and potent blocker of voltage-dependent sodium channels in motor nerves, causes skeletal muscle paralysis Narahashi et al (1964), Hille …

How Scientists Detect the Most Lethal Shellfish Toxin …

    https://www.kqed.org/science/1944148/how-scientists-detect-the-most-lethal-shellfish-toxin-youve-never-heard-of
    When ingested by humans, saxitoxin causes paralytic shellfish poisoning, or PSP, symptoms of which include tingling, numbness, and, if …

Purified Saxitoxin for Food Safety Applications | FDA

    https://www.fda.gov/science-research/licensing-and-collaboration-opportunities/purified-saxitoxin-food-safety-applications
    Saxitoxin is the parent compound in a family of natural toxins that can occur in seafood and can cause food borne illness. Highly purified saxitoxin is vital for the development, …

Neosaxitoxin - Wikipedia

    https://en.wikipedia.org/wiki/Neosaxitoxin
    Neosaxitoxin (NSTX) is included, as other saxitoxin-analogs, in a broad group of natural neurotoxic alkaloids, commonly known as the paralytic shellfish toxins (PSTs). The …

Molecule of the Month: SAXITOXIN

    https://www.bristol.ac.uk/Depts/Chemistry/MOTM/stx/saxi1.htm
    Saxitoxin has been used for the labelling, characterisation and isolation of various sodium channel components, and this has opened up new avenues for the study of various …

CDC | Case Definition: Saxitoxin Poisoning

    https://emergency.cdc.gov/agent/saxitoxin/casedef.asp
    Ingestion of saxitoxin can cause numbness of the oral mucosa as quickly as 30 minutes after exposure. In severe poisoning, illness typically progresses rapidly and may …

[Saxitoxins and tetrodotokxins as a new biological weapon]

    https://pubmed.ncbi.nlm.nih.gov/26449582/
    Abstract. Saxitoxins (STX) and tetrodotoxins (TTX) are a group of chemical compounds produced by certain species of marine algae and fish. Lethal dose for a human is about …

Tetrodotoxin, an Extremely Potent Marine Neurotoxin: …

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4626696/
    In fact, a binding protein for TTX as well as for saxitoxin (STX), another neurotoxin that blocks sodium channels, present in the plasma of pufferfish, may …



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