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Multiple Co-primary Endpoints: Medical and Statistical …

    https://journals.sagepub.com/doi/10.1177/009286150704100105
    Abstract. There are quite a few disorders for which regulatory agencies have required a treatment to demonstrate a statistically significant effect on multiple endpoints, each at …

Multiple Co-primary Endpoints: Medical and Statistical …

    https://link.springer.com/article/10.1177/009286150704100105
    Abstract. There are quite a few disorders for which regulatory agencies have required a treatment to demonstrate a statistically significant effect on multiple …

Multiple Co-primary Endpoints: Medical and Statistical …

    https://journals.sagepub.com/doi/full/10.1177/009286150704100105
    Multiple Co-primary Endpoints: Medical and Statistical Solutions: A Report from the Multiple Endpoints Expert Team of the Pharmaceutical Research and Manufacturers of …

Multiple Co-primary Endpoints: Medical and Statistical …

    https://www.semanticscholar.org/paper/Multiple-Co-primary-Endpoints%3A-Medical-and-A-Report-Offen-Chuang-Stein/245ad4aad5006492d6f0588a05c7468f0d2a91d9
    Multiple Co-primary Endpoints: Medical and Statistical Solutions: A Report from the Multiple Endpoints Expert Team of the Pharmaceutical Research and …

Multiple co-primary endpoints: medical and statistical solutions: a ...

    https://www.rtihs.org/publications/multiple-co-primary-endpoints-medical-and-statistical-solutions-report-multiple
    There are quite a few disorders for which regulatory agencies have required a treatment to demonstrate a statistically significant effect on multiple endpoints, each at the one-sided …

Multiple Co-primary Endpoints: Medical and Statistical …

    https://www.researchgate.net/publication/254087626_Multiple_Co-primary_Endpoints_Medical_and_Statistical_Solutions_A_Report_from_the_Multiple_Endpoints_Expert_Team_of_the_Pharmaceutical_Research_and_Manufacturers_of_America
    Multiple Co-primary Endpoints: Medical and Statistical Solutions: A Report from the Multiple Endpoints Expert Team of the Pharmaceutical Research and …

Evaluating co-primary endpoints collectively in clinical trials

    https://pubmed.ncbi.nlm.nih.gov/19219905/
    In this paper, statistical methods are developed to derive decision rules to evaluate co-primary endpoints collectively. The decision rules control the error rate of wrongly …

Multiple Endpoints in Clinical Trials Guidance for Industry

    https://www.fda.gov/regulatory-information/search-fda-guidance-documents/multiple-endpoints-clinical-trials-guidance-industry
    This guidance provides sponsors and review staff with the Agency’s thinking about the problems posed by multiple endpoints in the analysis and interpretation of …

Co-primary endpoints and multiple primary endpoints

    https://onbiostatistics.blogspot.com/2017/11/co-primary-endpoints-and-multiple.html
    The term used in this guidance to describe this circumstance of multiple primary endpoints is co-primary endpoints. Multiple primary endpoints become co …

Multiple Endpoints in Clinical Trials Guidance for …

    https://www.fda.gov/media/102657/download
    Multiple Endpoints in Clinical Trials Guidance for Industry Additional copies are available from: Office of Communications, Division of Drug Information Center for Drug Evaluation …



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