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Protein X-ray Crystallography and Drug Discovery …

    https://pubmed.ncbi.nlm.nih.gov/32106588/

    Protein Crystallography in Vaccine Research and …

      https://www.mdpi.com/1422-0067/16/6/13106
      The use of protein X-ray crystallography for structure-based design of small-molecule drugs is well-documented and includes several notable success stories. …

    Why Crystallography? - Structural Biology Facility - Mayo …

      https://www.mayo.edu/research/labs/structural-biology/crystallizing-macromolecules/why-crystallography
      X-ray crystallography is considered the most powerful method for determining 3D structures of biological macromolecules — such as proteins and nucleic acids — and …

    Protein Crystallography and Drug Discovery - ScienceDirect

      https://www.sciencedirect.com/science/article/pii/B9780123741943000305
      Protein crystals typically contain at least 30% and up to 80% (v/v) solvent (in fact, aque- ous crystallization buffer). 87 Only a fraction of the protein surface is involved …

    Protein Crystallography in Vaccine Research and …

      https://pubmed.ncbi.nlm.nih.gov/26068237/
      The use of protein X-ray crystallography for structure-based design of small-molecule drugs is well-documented and includes several notable success stories. …

    Crystallizing Science, One Protein at a Time …

      https://biochem.wisc.edu/news/2017/news-biochemistry-crystallography-2017-09-14
      It puts the “basic” in basic science. How ever you describe it, understanding protein structure and function through what’s called X-ray crystallography is an …

    Crystallography and protein-protein interactions: …

      https://pubmed.ncbi.nlm.nih.gov/19021571/
      Crystallography is commonly used for studying the structures of protein-protein complexes. However, a crystal structure does not define a unique protein-protein …

    Neutron Protein Crystallography: Advances in Methods …

      https://www.annualreviews.org/doi/abs/10.1146/annurev.bb.12.060183.001111
      Biomedical Data Science; Biomedical Engineering; Biophysics; ... THE APPLICATION OF NEUTRON CRYSTALLOGRAPHY TO THE STUDY OF DYNAMIC AND …

    Protein Crystallography: From Protein Structure to …

      https://www.creativebiomart.net/blog/protein-crystallography-from-protein-structure-to-protein-function/
      The function of a protein is encoded by its 3D structure. Protein crystallography is used as the major biophysical approach to investigate protein …

    The Applications & Principles of X-Ray …

      https://www.azom.com/article.aspx?ArticleID=18684
      X-ray crystallography is a powerful non-destructive technique for determining the molecular structure of a crystal. X-ray crystallography uses the principles of X-ray …



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