Sequential Medical Trials

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Sequential clinical trials—but not for beginners - The Lancet

https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(05)70347-0/fulltext

Sequential trials are pre-planned, repeated series of comparisons that are stopped as soon as a decision can be made as to whether one treatment can be regarded as superior to another, or that both are equally effective. Fewer patients, …

Sequential Methods for Clinical Trials - Wiley Online Library

https://onlinelibrary.wiley.com/doi/full/10.1002/9781118445112.stat04964

Investigators planning a clinical trial today have a wide range of sequential methods available to choose from, with software packages such as PEST 4 37, EaSt …

Sequential clinical trials in emergency medicine - PubMed

https://pubmed.ncbi.nlm.nih.gov/2393170/

Sequential statistical techniques provide a method for the analysis of clinical trials so that a reliable result is obtained with a minimum number of patients. In a sequential …

Designing Sequential Clinical Trials - Statsols

https://blog.statsols.com/designing-sequential-clinical-trials

Sequential designs are a very powerful and useful class of Adaptive trial designs that have become common in the clinical trial landscape. Due to the complex …

Group Sequential Design: Overview & Simple Definition

https://www.statisticshowto.com/group-sequential-design/

Group sequential trials are used in clinical trials. A group sequential design is a type of adaptive design where the number of patients isn’t set in advance. Patients are …

Sequential medical trials | PNAS

https://www.pnas.org/doi/10.1073/pnas.77.6.3135

A model for sequential clinical trials is discussed. Three proposed stopping rules are studied by the Monte Carlo method for small patient horizons and mathematically …

Sequential, Multiple Assignment, Randomized Trials …

https://d3c.isr.umich.edu/experimental-designs/sequential-multiple-assignment-randomized-trials-smarts/

The Sequential, Multiple Assignment, Randomized Trial (SMART) is an experimental design used to construct an optimized adaptive intervention. In the SMART experimental design, study participants …

DIFFERENT TYPES OF CLINICAL TRIALS - S.E.F.O.

https://www.scientific-european-federation-osteopaths.org/different-types-of-clinical-trials/

1) CLINICAL TRIAL: Carefully and ethically-designed experiment, in which participating subjects are assigned to the different modes of intervention simultaneously (in the same period of time), at random and are also …

Sequential clinical trials - ScienceDirect

https://www.sciencedirect.com/science/article/pii/0021968158902017

The sequential trials which have been published in the medical literature can be counted on your fingers. However, the current trend toward the controlled clinical trial …

Sequential medical trials - PubMed

https://pubmed.ncbi.nlm.nih.gov/363193/

Sequential medical trials Sequential medical trials Biomedicine. 1978 Sep;28 Spec No:40-1. Author P Armitage PMID: 363193 No abstract available Publication types …

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