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Sickle Cell Disease: A Review - PubMed
- https://pubmed.ncbi.nlm.nih.gov/35788790/
- Importance: Sickle cell disease (SCD) is an inherited disorder of hemoglobin, characterized by formation of long chains of hemoglobin when deoxygenated within …
Sickle Cell Anemia - PubMed
- https://pubmed.ncbi.nlm.nih.gov/29489205/
- Sickle cell anemia is the most common form of SCD, with a lifelong affliction of hemolytic anemia requiring blood transfusions, pain crises, and organ damage. Since …
Sickle Cell Disease | NEJM - New England …
- https://www.nejm.org/doi/full/10.1056/NEJMra1510865
- Estimates suggest that every year approximately 300,000 infants are born with sickle cell anemia, which is defined …
Sickle Cell Disease: Advances in Treatment | Ochsner Journal
- https://www.ochsnerjournal.org/content/18/4/377
- In 1927, Hahn and Gillespie had reported on the mechanism of sickle formation, observing that the sickle hemoglobin in its deoxygenated state assumed the characteristic shape, …
Sickle cell anemia - Diagnosis and treatment - Mayo Clinic
- https://www.mayoclinic.org/diseases-conditions/sickle-cell-anemia/diagnosis-treatment/drc-20355882
- The FDA recently approved this drug for treatment of sickle cell anemia. It helps in reducing the frequency of pain crises. Crizanlizumab (Adakveo). This drug, given …
CE: Understanding the Complications of Sickle Cell …
- https://journals.lww.com/ajnonline/Fulltext/2019/06000/CE__Understanding_the_Complications_of_Sickle_Cell.23.aspx
- The sickled blood cells break down prematurely, potentially producing anemia. Since they are rigid, they may become trapped in small blood vessels, triggering acute painful …
Sickle cell disease: a neglected chronic disease of …
- https://adc.bmj.com/content/100/1/48
- Sickle cell disease (SCD) is a single gene disorder causing a debilitating systemic syndrome characterised by chronic anaemia, acute painful episodes, organ infarction and …
Using the consolidated framework for implementation …
- https://journals.sagepub.com/doi/full/10.1177/17407745231154199
- Wynn L, Miller S, Faughnan L, et al. Recruitment of infants with sickle cell anemia to a Phase III trial: data from the BABY HUG study. Contemp Clin Trials 2010; 31 …
Sickle cell anemia - The American Journal of Medicine
- https://www.amjmed.com/article/0002-9343(50)90291-9/fulltext
- The clinical manifestations of fifty-four patients with sickle cell anemia admitted to the charity hospitals of this area during the past ten years are presented. Emphasis has been …
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