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Therapeutic siRNA: state of the art - Nature
- https://www.nature.com/articles/s41392-020-0207-x
- siRNA has innate advantages over small molecular therapeutics and monoclonal antibody drugs because siRNA executes its function by complete …
Small Interfering RNA (siRNA) Based …
- https://www.ncbi.nlm.nih.gov/books/NBK580472/
- Small interfering ribonucleic acid (siRNA) based therapies are newly approved therapeutics …
siRNA: Mechanism of action, challenges, and …
- https://pubmed.ncbi.nlm.nih.gov/34044011/
- The mechanism of action of small interfering RNA (siRNA) is based on post-transcriptional gene silencing. siRNA molecules are usually specific and efficient in the …
siRNA therapeutics: a clinical reality - PubMed
- https://pubmed.ncbi.nlm.nih.gov/31054052/
- Abstract. Since the revolutionary discovery of RNA interference (RNAi), a remarkable progress has been achieved in understanding and harnessing gene silencing …
Promising mRNA tech comes with regulatory, CMC …
- https://www.raps.org/news-and-articles/news-articles/2020/11/euro-convergence-regulatory-and-cmc-considerations
- Immunogenic response is possible with mRNA therapies for rare diseases, so manufacturers and regulatory professionals must be vigilant at all stages, since even …
Michael Molyneaux - Chief Medical Officer
- https://www.linkedin.com/in/michael-molyneaux-496ab230
- Sirnaomics is a biopharmaceutical company discovering and developing novel targeted therapeutics for critical human …
What is SiRNA? - News-Medical.net
- https://www.news-medical.net/life-sciences/What-is-SiRNA.aspx
- siRNA production is catalyzed by an enzyme known as the Dicer enzyme. This is a powerful tool in drug targeting and therapeutics development as it is used to …
Akero Therapeutics | Efruxifermin for NASH | Leadership
- https://akerotx.com/leadership/
- She brings over 15 years of experience in clinical and medical affairs across multiple therapeutic areas including GI, non-viral liver disease, and metabolic disease. Reshma …
Sirna Therapeutics Medical Affairs | Day of Difference
- https://dayofdifference.org.au/s-medical/sirna-therapeutics-medical-affairs.html
- siRNA has innate advantages over small molecular therapeutics and monoclonal antibody drugs because siRNA executes its function by complete Watson–Crick base pairing with …
Sirna Therapeutics - Wikipedia
- https://en.wikipedia.org/wiki/Sirna_Therapeutics
- Sirna Therapeutics, Inc. was a San Francisco, California based biotechnology company that explored the use of RNA interference in human disease therapy. Sirna's …
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