Spliceosome Research Medically Related

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Emerging roles of spliceosome in cancer …

https://link.springer.com/article/10.1007/s13238-021-00856-5

Precursor messenger RNA (pre-mRNA) splicing is catalyzed by an intricate ribonucleoprotein complex …

Emerging roles of spliceosome in cancer and immunity

https://pubmed.ncbi.nlm.nih.gov/34196950/

Recent studies have shown that some spliceosome gene mutations can result in immune dysregulation and notable phenotypes due to mis-splicing of immune-related genes. …

The biological function and clinical significance

https://biomarkerres.biomedcentral.com/articles/10.1186/s40364-020-00220-5

Spliceosome mutations have become the most interesting mutations detected in human cancer in recent years. The spliceosome, a large, dynamic …

Spliceosomopathies: Diseases and mechanisms - PubMed

https://pubmed.ncbi.nlm.nih.gov/32506634/

Abstract. The spliceosome is a complex of RNA and proteins that function together to identify intron-exon junctions in precursor messenger-RNAs, splice out the introns, and …

Romancing the Spliceosome to Fight Spinal …

https://www.nejm.org/doi/full/10.1056/NEJMcibr1409795

Original Article Jan 19, 2023 Aspirin or Low-Molecular-Weight Heparin for Thromboprophylaxis after a Fracture …

The impact of spliceosome mutations in MDS : …

https://journals.lww.com/hemasphere/Fulltext/2019/06002/The_impact_of_spliceosome_mutations_in_MDS.50.aspx

The treatment of SF-mutant patient-derived xenograft models with the spliceosome inhibitors E7107 13 and H3B-8800 20 has demonstrated the therapeutic potential of these …

Spliceosomes - Current Biology

https://www.cell.com/current-biology/fulltext/S0960-9822(14)01553-X

Spliceosomes are huge, multimegadalton ribonucleoprotein (RNP) complexes found in eukaryotic nuclei. They assemble on RNA polymerase II …

Spliceosome Research Medically Related | Day of Difference

https://dayofdifference.org.au/s-medical/spliceosome-research-medically-related.html

Emerging roles of spliceosome in cancer and immunity. https://pubmed.ncbi.nlm.nih.gov/34196950/ Recent studies have shown that some …

Spliceosome Database: a tool for tracking components …

https://academic.oup.com/nar/article/41/D1/D132/1075957

The spliceosome is the extremely complex macromolecular machine responsible for pre-mRNA splicing. ... Melissa S. Jurica, Spliceosome Database: a tool …

Spliceosome Medically Related | Day of Difference

https://dayofdifference.org.au/s-medical/spliceosome-medically-related.html

Spliceosome Medically Related data. Medical information at dayofdifference.org.au. Telephone (02) 8910 2000. Our Work. Critical Injury Research; Hospital Care Program; …

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