Survival In Medically Treated Patients With Homozygous B-Thalassemia

Survival in medically treated patients with homozygous …

https://pubmed.ncbi.nlm.nih.gov/8047081/

Patients in whom less than 33 percent of the serum ferritin values exceeded 2500 ng per milliliter had estimated rates of survival without cardiac disease of 100 percent after 10 years of chelation therapy and 91 percent after 15 years. Conclusions: The …

Survival in Medically Treated Patients with Homozygous …

https://www.nejm.org/doi/full/10.1056/NEJM199409013310903

Survival in Medically Treated Patients with Homozygous …

https://www.semanticscholar.org/paper/Survival-in-Medically-Treated-Patients-with-Olivieri-Nathan/7719924d1e7c164d25bc918c6185d1c4847219e9

Background The prognosis of patients with homozygous β-thalassemia (thalassemia major) has been improved by transfusion and iron-chelation therapy. We …

Survival in medically treated patients with homozygous …

https://www.semanticscholar.org/paper/Survival-in-medically-treated-patients-with-Olivieri-Nathan/dc897a64df27fcd2b7e3c537f782118da97c5208

With stepwise Cox modeling, only the proportion of ferritin measurements exceeding 2500 ng per milliliter affected cardiac disease-free survival (P < 0.001). Patients in whom less …

Evaluation of survival in medically treated patients with …

https://pubmed.ncbi.nlm.nih.gov/10150804/

Authors evaluating survival in a cohort of individuals with Thalassemia Major concluded the prognosis was excellent. This was based solely on observed mortality. When the cohort …

Beta Thalassemia - StatPearls - NCBI Bookshelf

https://www.ncbi.nlm.nih.gov/books/NBK531481/

Homozygosity or compound heterozygosity for beta-thalassemia mutations cause a more severe spectrum of anemias called beta-thalassemia intermedia and beta-thalassemia major. These two are …

Beta Thalassemia | Johns Hopkins Medicine

https://www.hopkinsmedicine.org/health/conditions-and-diseases/beta-thalassemia

Thalassemia minima is mild and causes no problems. But you will be a carrier of the disorder. Thalassemia intermedia can cause problems based on the severity of the …

Survival in medically treated patients with homozygous …

https://europepmc.org/article/MED/8047081

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β-Thalassemia Cardiomyopathy | Circulation: Heart Failure

https://www.ahajournals.org/doi/full/10.1161/CIRCHEARTFAILURE.109.913863

The 5-year survival of heart failure in patients with thalassemia major was similar to that of the regular heart failure population after the addition to the regular heart failure treatment of intensified …

Beta-Thalassemia - GeneReviews® - NCBI Bookshelf

https://www.ncbi.nlm.nih.gov/books/NBK1426/

Adults with beta-thalassemia are at increased risk for transplant-related toxicity due to an advanced phase of the disease and have a two-year overall survival of 80% and a two-year event-free …