Survival In Medically Treated Patients With Homozygous Beta-Thalassemia

Survival in medically treated patients with homozygous …

https://pubmed.ncbi.nlm.nih.gov/8047081/

Patients in whom less than 33 percent of the serum ferritin values exceeded 2500 ng per milliliter had estimated rates of survival without cardiac disease of 100 percent after 10 years of chelation therapy and 91 percent after 15 years. Conclusions: The …

Survival in Medically Treated Patients with Homozygous …

https://www.nejm.org/doi/full/10.1056/NEJM199409013310903

Evaluation of survival in medically treated patients with …

https://pubmed.ncbi.nlm.nih.gov/10150804/

Authors evaluating survival in a cohort of individuals with Thalassemia Major concluded the prognosis was excellent. This was based solely on observed mortality. When the cohort …

Survival in Medically Treated Patients with Homozygous …

https://www.semanticscholar.org/paper/Survival-in-Medically-Treated-Patients-with-Olivieri-Nathan/7719924d1e7c164d25bc918c6185d1c4847219e9

Background The prognosis of patients with homozygous β-thalassemia (thalassemia major) has been improved by transfusion and iron-chelation therapy. We …

Survival in medically treated patients with homozygous …

https://reference.medscape.com/medline/abstract/8047081

With stepwise Cox modeling, only the proportion of ferritin measurements exceeding 2500 ng per milliliter affected cardiac disease-free survival (P < 0.001). Patients in whom …

Beta Thalassemia - StatPearls - NCBI …

https://www.ncbi.nlm.nih.gov/books/NBK531481/

Homozygosity or compound heterozygosity for beta-thalassemia mutations cause a more severe spectrum of anemias called beta-thalassemia intermedia and beta …

Beta-Thalassemia - GeneReviews® - NCBI …

https://www.ncbi.nlm.nih.gov/books/NBK1426/

Individuals with thalassemia major have severe anemia and hepatosplenomegaly; they usually come to medical attention within the first two years of life. …

Survival in medically treated patients with homozygous …

https://europepmc.org/article/MED/8047081

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β-Thalassemia Cardiomyopathy

https://www.ahajournals.org/doi/10.1161/CIRCHEARTFAILURE.109.913863

In the mid-1960s, only 37% of patients in a small group of 41 patients with thalassemia major were alive at the age of 16 years. 4 In contrast, a 95% survival …

About Thalassemia - The Cooley's Anemia Foundation

https://www.thalassemia.org/learn-about-thalassemia/about-thalassemia/

Individuals born with alpha thalassemia major are treated with lifelong blood transfusions and other medical care. (UCSF Benioff Children’s Hospital has created two brochures on …