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Bone and Tendon Graft Substitutes and Adjuncts

    https://www.aetna.com/cpb/medical/data/400_499/0411.html
    Technology: P-15 bone putty (i-Factor) is a synthetic osteoconductive bone substitute that is approved for use in cervical fusion procedures. The first step in the bone formation process is cell attachment. Osteogenic precursor cells bind to P-15, then a natural signaling cascade occurs that leads to new bone formation (CMS, 2016).

Bone, Cartilage and Ligament Graft Substitutes - Cigna

    https://static.cigna.com/assets/chcp/pdf/coveragePolicies/medical/mm_0118_coveragepositioncriteria_recombinant_human_bone_morphogenetic_protein.pdf
    Synthetic bone grafts and demineralized bone matrices (DBM) are considered Class II materials and fall under the FDA 510(k) regulatory process and upon approval are …

New method heals skeletal injuries with synthetic bone

    https://www.sciencedaily.com/releases/2021/01/210119114332.htm
    Researchers have developed a way of combining a bone substitute and drugs to regenerate bone and heal severe fractures in the thigh or shin bone. The study …

New method heals skeletal injuries with synthetic bone - Medical …

    https://medicalxpress.com/news/2021-01-method-skeletal-injuries-synthetic-bone.html
    Researchers at Lund University in Sweden, in collaboration with colleagues in Dresden, Germany, have developed a way of combining a bone substitute and drugs to …

Cigna Medical Coverage Policy - AAPC

    https://www.aapc.com/codes/webroot/upload/general_pages_docs/document/mm_0118_coveragepositioncriteria_recombinant_human_bone_morphogenetic_protein.pdf
    Bone grafts can be harvested from the patient (autograft), a cadaver (allograft), or they can be synthetic. The composition of allograft and synthetic bone graft …

SURG.00011 Allogeneic, Xenographic, Synthetic, …

    https://www.anthem.com/dam/medpolicies/abc/active/policies/mp_pw_a053309.html
    Biobrane, a synthetic product composed of a silicone film bonded to a nylon fabric base, has been approved through the FDA’s PMA process. Data regarding the use …

Surgical Treatment for Spine Pain - UHCprovider.com

    https://www.uhcprovider.com/content/dam/provider/docs/public/policies/comm-medical-drug/surgical-treatment-spine-pain.pdf
    Facet Fusion : A minimally invasive back procedure that uses specially designed bone dowels made from allograft material (donated cortical bone) that are inserted into the …

Osteochondral Autografts (Mosaicplasty, OATS)

    https://www.aetna.com/cpb/medical/data/600_699/0637.html
    The Institute for Clinical Effectiveness and Health Policy (Pichon-Riviere et al, 2006) evaluated the literature on the effectiveness of OATS and mosaicplasty on ankle …

Articular Cartilage Defect Repairs - UHCprovider.com

    https://www.uhcprovider.com/content/dam/provider/docs/public/policies/comm-medical-drug/articular-cartilage-defect-repairs.pdf
    underlying bone marrow after stimulation to provide dense extracellular matrix intended to enhance biomechanical stability and promote chondrogenesis (Hayes, 2018). Autografts: …

Medical Policy Total Ankle Replacement

    https://www.bluecrossma.org/medical-policies/sites/g/files/csphws2091/files/acquiadam-assets/193%20Total%20Ankle%20Replacement%20prn.pdf
    Severe malalignment (e.g., > 15 degrees) not correctable by surgery OR Active ankle joint infection OR Peripheral vascular disease, OR Charcot neuroarthropathy. Total …



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