Synthetic Mammalian Gene Circuits For Biomedical Applications

Synthetic mammalian gene circuits for biomedical …

https://pubmed.ncbi.nlm.nih.gov/24466575/

Synthetic biology is the science of reassembling cataloged and standardized biological items in a systematic and rational manner to create and engineer functional biological designer devices, systems and organisms with novel and useful, preferably therapeutic functions. …

Synthetic mammalian gene circuits for biomedical …

https://www.sciencedirect.com/science/article/pii/S1367593113001749

Synthetic mammalian gene circuits for biomedical …

https://www.sciencedirect.com/science/article/abs/pii/S1367593113001749

This review covers the most recent synthetic mammalian circuits designed for therapy of diseases such as metabolic disorders, cancer, and immune disorders. We …

Synthetic gene circuits for the detection, elimination and …

https://www.nature.com/articles/s41551-018-0215-0

Fig. 1: Development process for gene circuits addressing medical conditions. (1) The design of customized gene circuits begins with the identification of relevant …

Synthetic therapeutic gene circuits in mammalian cells

https://www.sciencedirect.com/science/article/pii/S0014579314003640

Synthetic biologists capitalise on naturally existing biomolecules, including functional DNA, RNA, and proteins from a range of organisms such as microbes, plants, …

Mammalian synthetic biology: emerging medical …

https://pubmed.ncbi.nlm.nih.gov/25808341/

A comprehensive list of ON-OFF switches, categorized into transcriptional, post-transcriptional, translational and post-translational, is presented in the first sections. …

Synthetic mammalian gene circuits for biomedical …

https://www.semanticscholar.org/paper/Synthetic-mammalian-gene-circuits-for-biomedical-Ye-Aubel/c8af02f06b5afc61c173fa48108b1c607b5b8396

New emerging medical applications of the rapidly evolving field of mammalian synthetic biology and the applicability of synthetic gene networks to drug …

Synthetic mammalian gene circuits for biomedical …

https://www.researchgate.net/publication/259920929_Synthetic_mammalian_gene_circuits_for_biomedical_applications

Synthetic biology offers a bottom-up approach for exploring the design and function of biological systems, and for engineering cells and organisms to address a …

Synthetic therapeutic gene circuits in mammalian cells

https://pubmed.ncbi.nlm.nih.gov/24844435/

In the emerging field of synthetic biology, scientists are focusing on designing and creating functional devices, systems, and organisms with novel functions by …

[Research progress of mammalian synthetic biology in …

https://pubmed.ncbi.nlm.nih.gov/28941342/

In this review, we describe the recent advances of mammalian synthetic biology for the treatment of diseases. We introduce common tools and design principles …