Tigecycline More Medical_Authorities

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Tigecycline - Infectious Diseases - Merck Manuals …

https://www.merckmanuals.com/professional/infectious-diseases/bacteria-and-antibacterial-drugs/tigecycline

Tigecycline has a large volume of distribution ( > 12 L/kg), penetrating well into bone, lung, liver, and kidney tissues. However, because of its extensive distribution into tissue, blood levels are low, so tigecycline is probably not a good choice for patients with bacteremia …

Tigecycline Uses, Side Effects & Warnings - Drugs.com

https://www.drugs.com/mtm/tigecycline.html

Tigecycline is an antibiotic that fights bacteria in the body. Tigecycline is used to treat many different bacterial infections of the skin or the digestive system, as well as …

Tigecycline: A New Glycylcycline for Treatment of …

https://academic.oup.com/cid/article/41/Supplement_5/S303/288990

Tigecycline is a new semisynthetic glycylcycline for the treatment of serious infections. Of the glycylcyclines, tigecycline is the most studied and appears to hold …

Tigecycline - LiverTox - NCBI Bookshelf

https://www.ncbi.nlm.nih.gov/books/NBK547888/

Like other tetracyclines, tigecycline is a broad spectrum bacteriostatic agent that acts by binding to …

Tigecycline (Tygacil) - University of Nebraska Medical …

https://www.unmc.edu/intmed/divisions/id/asp/protected-antimicrobials/tigecycline.html

While tigecycline has excellent tissue penetration, it also has very low plasma concentrations, suggesting that it is not an ideal agent for treatment of bacteremia or …

Tigecycline: Package Insert / Prescribing …

https://www.drugs.com/pro/tigecycline.html

In a single-dose study, Tigecycline 100 mg was administered to subjects prior to undergoing elective surgery or medical procedure for tissue extraction. …

Tigecycline: a novel broad-spectrum antimicrobial - PubMed

https://pubmed.ncbi.nlm.nih.gov/17519296/

Data synthesis: A tigecycline 100 mg intravenous loading dose followed by an intravenous infusion of 50 mg every 12 hours was shown in clinical trials to be as effective as …

Tigecycline: a glycylcycline antimicrobial agent - PubMed

https://pubmed.ncbi.nlm.nih.gov/16982286/

In vitro, tigecycline exhibits activity against a wide range of clinically significant gram-positive and gram-negative bacteria, including multidrug-resistant strains (eg, oxacillin …

Tigecycline – Injection products | FDA

https://www.fda.gov/drugs/development-resources/tigecycline-injection-products

Tigecycline – Injection products FDA-Identified Interpretive Criteria S = Susceptible; I = Intermediate; R = Resistant For disk diffusion, use paper disks …

Tigecycline (Tygacil ): increased mortality in clinical trials

https://www.gov.uk/drug-safety-update/tigecycline-tygacil-increased-mortality-in-clinical-trials

tigecycline is approved only for treatment of complicated skin and soft tissue infections and complicated intra-abdominal infections tigecycline should only be used in …

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