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Tenecteplase (TNK) Treatment for Stroke | UC Health

    https://www.uchealth.com/en/treatments/tnk
    Tenecteplase (TNK) is a protein that can break up blood clots. It is a powerful blood-thinning medication administered to patients experiencing a stroke caused by a sudden …

Study of Tenecteplase (TNK) in Acute Ischemic Stroke …

    https://www.ninds.nih.gov/health-information/clinical-trials/study-tenecteplase-tnk-acute-ischemic-stroke-tnk-s2b
    To date, the only scientifically-proven and FDA-approved treatment for acute stroke is the clot-busting drug, tissue plasminogen activator (tPA). A newer clot-busting …

tPA and TNK Mix-ups: Clearing Up the Confusion

    https://www.medscape.com/viewarticle/850514
    The take-away message is that "tPA" is the abbreviation for the drug class tissue plasminogen activators, which includes drug products Activase, Retavase, and …

Making the Switch From Alteplase to Tenecteplase for …

    https://consultqd.clevelandclinic.org/making-the-switch-from-alteplase-to-tenecteplase-for-acute-ischemic-stroke/

    Study of Tenecteplase (TNK) in Acute Ischemic Stroke …

      https://clinicaltrials.gov/ct2/show/NCT00252239
      Stroke is the third leading cause of death and a leading cause of adult disability in the United States and worldwide. To date, the only scientifically-proven and …

    TNKase® Acute Myocardial Infarction Treatment

      https://www.tnkase.com/
      The only lytic delivered as a 5-second IV bolus for the treatment of acute myocardial infarction (AMI), TNKase ® (Tenecteplase) enables you to intervene quickly. 5-second …

    Tenecteplase Thrombolysis for Acute Ischemic Stroke

      https://www.ahajournals.org/doi/10.1161/STROKEAHA.120.029749
      The TAAIS (Tenecteplase versus Alteplase for Acute Ischaemic Stroke), also referred to as the Australian-TNK trial, randomized patients with middle cerebral artery …

    Tenecteplase (TNK) for treatment of Acute Ischemic Stroke

      https://www.mainestroke.org/post/tenecteplase-tnk-for-treatment-of-acute-ischemic-stroke
      TNK is a bioengineered variant of naturally occurring tPA, an endogenous enzyme that promotes the breakdown of blood clots. Molecular changes to TNK make it …

    TNKase® Dosing Guidelines

      https://www.tnkase.com/dosing-and-administration/dosing-guidelines.html
      TNKase is approved for IV administration only. The recommended total dose should not exceed 50 mg. Single-bolus TNKase includes a 5-tiered weight-based dosing schedule to match dose to patient weight. The …

    TNK Injection: Uses & Side Effects | Cleveland Clinic

      https://my.clevelandclinic.org/health/drugs/20030-tenecteplase-tnk-tpa-injection
      TENECTEPLASE (TEN neck te place) is used to dissolve blood clots that form in certain blood vessels. This medicine is used when a blood clot in a heart artery causes a heart …



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