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Guidance for Industry - Food and Drug Administration

    https://www.fda.gov/media/86377/download
    review of new drugs2 to address unmet medical need in the treatment of a serious or life- threatening 3 condition: fast track designation, breakthrough therapy designation, accelerated

Expedited Programs for Serious Conditions––Drugs and …

    https://www.fda.gov/regulatory-information/search-fda-guidance-documents/expedited-programs-serious-conditions-drugs-and-biologics
    The following four FDA programs are intended to facilitate and expedite development and review of new drugs to address unmet medical need in the treatment …

Regulatory pathways and approaches to unmet …

    https://www.fda.gov/media/99377/download
    ‘unmet medical needs’ means a condition for which there exists no satisfactory method of diagnosis, prevention or treatment authorised in the Community or, even if such a method …

Antibacterial Therapies for Patients With an Unmet …

    https://www.fda.gov/regulatory-information/search-fda-guidance-documents/antibacterial-therapies-patients-unmet-medical-need-treatment-serious-bacterial-diseases-questions
    Issued by: Center for Drug Evaluation and Research, Office of New Drugs The Food and Drug Administration (FDA or Agency) is announcing the availability of a …

Antibacterial Therapies for Patients With an Unmet …

    https://www.fda.gov/regulatory-information/search-fda-guidance-documents/antibacterial-therapies-patients-unmet-medical-need-treatment-serious-bacterial-diseases
    Specifically, the guidance explains the FDA’s current thinking about possible streamlined development programs and clinical trial designs for antibacterial drugs to …

Unmet medical need - National Institutes of Health

    https://toolkit.ncats.nih.gov/glossary/unmet-medical-need/
    An unmet medical need is a condition or symptom whose treatment or diagnosis is not addressed adequately by available therapy. An unmet medical need includes an …

2018 FDA/NCATS Report on Unmet Medical Device …

    https://www.fda.gov/industry/humanitarian-use-device-hud-designation-program/2018-fdancats-report-unmet-medical-device-needs-patients-rare-diseases
    Summary : The FDA and the NIH National Center for Advancing Translational Sciences (NCATS)/Office of Rare Diseases Research (ORDR) conducted this needs assessment …

Trial Considerations for Unmet Need - Food and …

    https://www.fda.gov/media/99304/download
    Treatment•mechanism(s)If to of resistance in patients be patient needs available before new of antibacterialemergence of drug the development high levels of …

Contents Page i - Food and Drug Administration

    https://www.fda.gov/media/111309/download
    understand unmet medical device needs for rare diseases; generate meaningful data to inform patients, practitioners, policymakers, and device developers on the needs, …

Future unmet medical need as a guiding principle for

    https://pubmed.ncbi.nlm.nih.gov/31233729/
    'Unmet medical need' is a widely used term in the healthcare sector but a common definition does not exist. The current standard of care determines the current unmet …



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