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Vioxx (rofecoxib) Questions and Answers | FDA
- https://www.fda.gov/drugs/postmarket-drug-safety-information-patients-and-providers/vioxx-rofecoxib-questions-and-answers
- Vioxx is a COX-2 selective nonsteroidal anti-inflammatory drug (NSAID). Vioxx is also related to the nonselective NSAIDs , such as ibuprofen and naproxen. Vioxx is a …
Timeline: The Rise and Fall of Vioxx : NPR - NPR.org
- https://www.npr.org/2007/11/10/5470430/timeline-the-rise-and-fall-of-vioxx
- November 1998: Merck asks the Food and Drug Administration (FDA) for approval of Vioxx, having tested the drug on 5,400 subjects in eight studies. January …
The Lessons of Vioxx — Drug Safety and Sales | NEJM
- https://www.nejm.org/doi/full/10.1056/NEJMp058136
- By the time of rofecoxib's withdrawal from the market in September 2004, after a placebo-controlled study confirmed its cardiovascular risk, more than 100 million …
Study linking Vioxx to heart problems finally published
- https://www.cbc.ca/news/science/study-linking-vioxx-to-heart-problems-finally-published-1.534735
- Vioxx, the anti-inflammatory drug taken off the market last fall because of safety concerns, could have caused thousands of heart problems and even deaths in the …
What have we learnt from Vioxx? - PMC - National …
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1779871/
- Rofecoxib (Vioxx) was introduced by Merck in 1999 as an effective, safer alternative to non-steroidal anti-inflammatory drugs for the treatment of pain associated …
Clinical Trials in the Wake of Vioxx | Circulation
- https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.105.604512
- The possibility of cardiac toxicity in human trials was recognized in the Vioxx Gastrointestinal Outcomes Research (VIGOR) trial. 4 Meta-analyses, database studies, …
Vioxx: The Downfall of a Drug : NPR
- https://www.npr.org/series/5033105/vioxx-the-downfall-of-a-drug
- Study: Health Risk Remains a Year After Quitting Vioxx May 12, 2006 • New results from a large scientific study show that the risk of heart problems and death from …
Vioxx International Medical Meeting Study David Graham
- https://dayofdifference.org.au/v-medical/vioxx-international-medical-meeting-study-david-graham.html
- The controversial study, which was led by FDA scientist David Graham, was the major impetus for the debate that has raged since last fall over the safety of Vioxx …
Vioxx International Medical Meeting Study | Day of Difference
- https://dayofdifference.org.au/v-medical/vioxx-international-medical-meeting-study.html
- In January 1999, Merck launched its largest study yet of rofecoxib, the Vioxx gastrointestinal outcomes research (VIGOR) study. The study was intended to expand …
VIOXX – Merck–MEDCO – a case study – Alliance for …
- https://ahrp.org/vioxx-merck-medco-a-case-study/
- VIOXX – Merck–MEDCO – a case study . Wed, 13 Oct 2004 . Vioxx: A case study in how a lethal drug is marketed and dispensed – without MINIMAL safeguards to …
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